چکیده مقاله
In this study, PAMAM polyamidoamine dendrimers were utiliezed as a drug delivery system of curcumin as a model drug The PAMAM dendrimers were studied by DLS to assess the chemical strucutre and size of the dendrimers in the presence of curcumin UV spectophotometry was also used to investigate the release profile of curcumin According to the obtained results, PAMAM dendrimers have the particle size of 43 and 212 nm before and after curcumin loading, respectively It also reveals a significant loading capacity of nearly 80% of curcumin, and it shows sustain release capacity for curcumin
کلیدواژهها
نویسندگان
Naeim Janatsharifi
Polymer and Color Engineering Department, Amirkabir University of Technology
Shahab Bagheri-Khoulenjani
Polymer and Color Engineering Department, Amirkabir University of Technology
Somaye Akbari
Textile Engineering Department, Amirkabir University of Technology
شیوه ارجاع
Janatsharifi, Naeim and Bagheri-Khoulenjani, Shahab and Akbari, Somaye,1402,Drug release study of curcumin loaded PAMAM dendrimers,6th International Conference on Technology Development in Chemical Engineering,Tehran
ارائهشده در
مجموعه مقالات ششمین کنفرانس بین المللی توسعه فناوری در مهندسی شیمی31 اردیبهشت 1402 · تهران