چکیده مقاله
Introduction: Thyroid hormones affect the testes in different ways and various cell types, including Leydig, Sertoli and germ cells Deficiency of thyroid hormones leads to alterations in testicular function, including abnormalities of seminal fluid This systematic review with meta analysis aimed to compare hypothyroidism and semen quality parameters such as sperm count, motility, and morphology Materials and Methods: literature search was performed to identify eligible studies in the PubMed, Scopus, Embase, and Web of Science databases without restriction by region or language A total of 7 studies that met the eligibility criteria, and the collected data were analyzed using Comprehensive Meta Analysis V3 software for meta analysis Results: Finally, 6 studies with a total of 3497 participants were identified Cases of subclinical hypothyroidism had statistically significant decreases in total sperm count SMD: 0 75, 95% CI: 1 29 to 0 21 , normal sperm morphology SMD: 0 99, 95% CI: 2 12 to 0 12 , and progressive sperm motility SMD: 1 56, 95% CI: 2 78 to 0 34 compared with control groups Conclusion: Thus, scientific evidence suggests that semen quality parameters are altered in Hypothyroidism patients compared to healthy controls Therefore, despite of other factors, hypothyroidism may play an essential role in changing spermatogenesis and the development of infertility in men
کلیدواژهها
نویسندگان
Mohammad Mehdi Abdi
Student Research Committee, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
Seyed Sobhan Bahreiny
Department of Medical Physiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Mohammad-Navid Bastani
Department of Virology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Hamid Ghorbani
Student Research Committee, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
Mehdi Zahedian
Student Research Committee, Ahvaz Jundishapur University of Medical Science, Ahvaz, Iran
شیوه ارجاع
Abdi, Mohammad Mehdi and Bahreiny, Seyed Sobhan and Bastani, Mohammad-Navid and Ghorbani, Hamid and Zahedian, Mehdi,1401," Effects of subclinical hypothyroidism on sperm quality parameter: A Systematic Review and Meta-Analysis." Running title: Meta-analysis of the Association between hypothyroidism and sperm quality parameter.,9th international conference on new findings in obstetrics, gynecology, childbirth and infertility
ارائهشده در
مجموعه مقالات نهمین کنفرانس بین المللی یافته های نو در مامایی، زنان، زایمان و نازایی19 اسفند 1401