چکیده مقاله
Adrenocortical tumour is rare in children We report on a female infant with adrenocorticalcarcinoma presenting with pseudoprecocious puberty at the age of two She had a history ofgradually increasing public hair growth after birth Physical examination showed signs ofvirilisation such as pubic hair growth and hirsutism with evidence of facial hair growth Onbiochemical evaluation, DHEA S, 17 OH progesterone, and testosterone levels were elevated Anabdominopelvic spiral computed tomography CT scan with intravenous contrast identified awell defined heterogeneously enhanced mass with areas of necrosis in the right adrenal gland anddownward displacement of the underlying kidney There was no evidence of distant metastasis onCT imaging An exploratory laparotomy was performed in which a large, haemorrhagic andnecrotic mass in the right adrenal gland with pressure effect on right liver lobe and signs ofthrombosis in the inferior vena cava was detected Pathologic examination confirmed theadrenocortical carcinoma She received eight cycles of adjuvant chemotherapy with Carboplatin,Etoposide, and Doxorubicin regimens and underwent follow up visits thereafter in which no signof recurrence was observed In conclusion, adrenocortical carcinomas are rare in children, but theyshould be considered in any child presenting with signs of pseudoprecocious puberty
کلیدواژهها
نویسندگان
Farid Ghazizadeh
Assistant Professor of Pediatric Hematology and Oncology, Urmia University of Medical Science,Urmia, Iran
maryam Ebadi
Shahid Beheshti Medical University, Tehran, Iran
Samin Alavi
Shahid Beheshti Medical University, Tehran, Iran
شیوه ارجاع
Ghazizadeh, Farid and Ebadi, maryam and Alavi, Samin,1401,Adrenocortical carcinoma presenting with heterosexual pseudo precociouspuberty shortly after birth: case report and review,The 12th International Conference on Health, Treatment and Health Promotion
ارائهشده در
مجموعه مقالات دوازدهمین کنفرانس بین المللی بهداشت، درمان و ارتقای سلامت22 اسفند 1401