چکیده مقاله
Environmental concerns and the growing urgency to address climate change have led to the development of sustainable alternatives to fossil fuels and manufactured chemicals Microbial systems, with their inherent biosynthetic capabilities, offer promising avenues to achieve this goal This review focuses on the coupling of systems and synthetic biology to manipulate microbial phenotypes to produce chemicals that can consume petroleum derived analogues and contribute to the advancement of green biotechnology The integration of artificial intelligence with metabolic engineering for the precise design and generation of biosynthetic pathways is also discussed, along with the identification of current hot spots and suggestions for optimizing biological systems, thereby moving the field of chemical biology towards sustainable chemical production Climate change and the reliance on petroleum industries have intensified the need for sustainable chemical production Recent advances in metabolic engineering and synthetic biology tools have accelerated the design and fabrication of microbial cell factories through rapid design, build, test, and learn cycles In addition, various systems biology tools, such as genome scale metabolic models GEMs , machine learning ML assisted pathway design, and deep learning DL based enzyme design, have been developed to enhance the potential of metabolic systems
کلیدواژهها
نویسندگان
Fatemeh Akbari
مقاله Strategy in sustainable biochemical engineering and synthesis through microbial systems
شیوه ارجاع
Akbari, Fatemeh,1403,Strategy in sustainable biochemical engineering and synthesis through microbial systems,Third International Congress for Chemical Engineering and Petroleum Industry students,Tehran
ارائهشده در
مجموعه مقالات سومین کنگره بین المللی دانشجویان مهندسی شیمی و صنعت نفت29 آبان 1403 · تهران