چکیده مقاله
Acrylate epoxidized soybean oil has showed great promise in biological applications, includingtissue engineering However, this material has limited mechanical strength and a rapidbiodegradation rate, limiting its potential to replicate and support a variety of hard tissues,including bone Furthermore, one of its downsides is the unique heat treatment procedure used withpoly glycerol co diacid To circumvent these constraints, polyethylene glycol fragments are firstcross linked with the main PGAz branch, yielding UV curable PGAz g GMA PGAG resin Then,polyethylene glycol, nanohydroxyapatite, and Cloisite Na nano clay are combined to createacrylate polyethylene glycol epoxidized soybean oil nanocomposites that are cross linked with lightand have effective qualities for mimicking various hard tissues Our findings indicate that allnanocomposites have a semi crystalline structure with β phase polyethylene glycol agent Thesescaffolds have maximal tensile strength and elongation at break points of 15 24 MPa, 13 15 MPa,and 50 65%, respectively, which fulfill the criteria of bone spongy tissue support The addition ofnanofillers increases the hydrophilic characteristic of the scaffolds while also marginallyaccelerating biodegradation In addition, it demonstrates that these scaffolds have no substantialcytotoxicity in vitro Our results indicate that the acrylate polyethylene glycol epoxidized soybeanoil combination and its nanocomposites might be a promising choice for hard tissues, particularlyspongy bone tissues
کلیدواژهها
نویسندگان
Hooriyeh Hadian
Islamic Azad University, Central Tehran Branch
AliAkbar Azodi
Islamic Azad University Science and Research Branch
Mohammad Nazari
Hooriyeh Hadian Islamic Azad University, Central Tehran BranchAliAkbar Azodi Islamic Azad University Science and Research BranchVahid Pirouz far
Vahid Pirouz far
Hooriyeh Hadian Islamic Azad University, Central Tehran BranchAliAkbar Azodi Islamic Azad University Science and Research BranchMohammad Nazari
شیوه ارجاع
Hadian, Hooriyeh and Azodi, AliAkbar and Nazari, Mohammad and Pirouz far, Vahid,1403,The synthesis of tissue engineering film based on acrylate-polyethylene glycolepoxidized soybean oil in the presence of nano chitosan,Third International Congress for Chemical Engineering and Petroleum Industry students,Tehran
ارائهشده در
مجموعه مقالات سومین کنگره بین المللی دانشجویان مهندسی شیمی و صنعت نفت29 آبان 1403 · تهران