چکیده مقاله
Human papillomavirus HPV is the most commonly diagnosed sexually transmitted infection and a necessary etiological agent of cervical cancer Persistence of HPV in cervical cells leads to structural changes in DNA and inhibition of tumor suppressor genes Up to 10% of women aged ≥30 years are estimated to carry persistent HPV infections, and these women are considered at highest risk for the development of cervical cancer In recent years, attention paid to micronutrients in gynecology has increased, especially regarding Human papillomavirus HPV infection That One of these micronutrients is vitamin D Vitamin D deficiency and its relationship with diseases have been an important public health problem that has been studied very much in recent years Sufficient levels of vitamin D offer protection against certain infectious diseases, while suboptimal levels of vitamin D correlate with an increased risk and severity of disease Our objective was to evaluate whether vitamin D deficiency is associated with cervical human papilloma virus HPV infection Methods:This article reviews the literature published until 2013 2023 in Scopus and PubMed databases by using keywords HPV DNA infection, vitamin D, 25 dihydroxyvitamin D, in the title, abstract and keywords Results: The main findings of this study showed that different results have been reported Some studies did not find any relationship between the lack of vitamin D with different markers with the increase in the prevalence of HPV and the removal of warts, but some studies also found a significant relationship between the decrease in the serum level of vitamin D and the increase in HPV was observed Serum vitamin D deficiency was significantly associated with positive high risk HPV infection of the cervix The results showed that a high level of vitamin D is effective in the short term durability of lesions Also, direct injection of vitamin D in lesions has been effective Conclusion:According to the contradictory findings of the studies, it is not possible to make a definite conclusion and it is suggested that more studies be conducted in this field
کلیدواژهها
نویسندگان
Hamide Hajnasiri
Msc of midwifery, faculty member of nursing & midwifery school, Qazvin University of Medical Sciences, Iran
Farnoosh Moafi
Msc of midwifery, faculty member of nursing & midwifery school, Qazvin University of Medical Sciences, Iran
Marziyeh Najar Mohiabadi
Msc of midwifery, faculty member of nursing & midwifery school, Rafsanjan University of Geriatric Care Research Center, Rafsanjan, Iran
شیوه ارجاع
Hajnasiri, Hamide and Moafi, Farnoosh and Najar Mohiabadi, Marziyeh,1402,The role of vitamin d in prevention and treatment HPV,The 11th International Conference on New Findings in Obstetrics, Women, Childbirth and Infertility
ارائهشده در
مجموعه مقالات یازدهمین کنفرانس بین المللی یافته های نو در مامایی، زنان، زایمان و نازایی19 آبان 1402