چکیده مقاله
Hydroxychloroquine HCQ is an anti malaria drug; its antiviral properties are controversial, and some in vitro studies approved its antiviral effects Many efforts have been made to prevent and treat COVID 19 infections, but effective drugs for complete eradication of COVID 19 have not been found yet, and all of them are supportive We try to review some new aspects of HCQ efficacy in the prevention and treatment of COVID 19 infection Also, some data from recent clinical trials were analyzed It has been shown that HCQ may improve some symptoms of patients, but in severe or critical stages did not have significant therapeutic effects and did not reduce the rate of mortality In the present review article, we explained some results of recent researches, including clinical trials about the effects of HCQ in the prevention and treatment of COVID 19 infection Some studies revealed HCQ beneficial effects in outpatients, and some data showed its hazardous impacts on the heart It was suggested that the dose of administration must be adjusted and monitored correctly; furthermore, the levels of some myocardial biomarkers such as troponin must be measured in moderate to severe COVID 19 infections
کلیدواژهها
نویسندگان
Amin Ataie
Department of Toxicology and Pharmacology, School of Medicine, Babol University of medical Sciences, Babol, Iran
Razieh Mansouri
Department of Toxicology and Pharmacology, School of Medicine, Babol University of medical Sciences, Babol, Iran
Hossein Khaleghzadeh-Ahangar
Department of Physiology, School of Medicine, Babol University of Medical Sciences, Babol, Iran Immunoregulation Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
Ramin Ataee
Pharmaceutical sciences research center, Hemoglobinopathy institute, Mazandaran University of medical sciences, Sari, Iran
Fatemeh Alibabaei
Department of Toxicology and Pharmacology, School of Medicine, Babol University of medical Sciences, Babol, Iran
شیوه ارجاع
Ataie, Amin and Mansouri, Razieh and Khaleghzadeh-Ahangar, Hossein and Ataee, Ramin and Alibabaei, Fatemeh,1401,Prophylactic Effect of Chloroquine and Hydroxychloroquine for COVID-19 Treatment,10th International Conference on Health, Treatment and Health Promotion
ارائهشده در
مجموعه مقالات دهمین کنفرانس بین المللی بهداشت،درمان و ارتقای سلامت16 تیر 1401