چکیده مقاله
Azam Ghorbani Assistant Professor of Islamic Azad University of Saveh Department of Chemistry, Collage of Technology and Engineering, Saveh Branch, Islamic Azad University, Saveh, Iran a ghorbani@iau saveh ac ir In This study three phase hollow fibers liquid phase micro extraction LPME method for preconcentration of Imipramin from biological sample was used Micro extraction application were evaluted based on porous hollow fibers by extraction with a pH gradient Imipramin is an antidepressant which extracted from the aqueous solution donor phase into an organic phase in the porse of the hollow fiber and continues to extract back to a second aqueous solution that is placed inside the hollow fiber The extracted analyte with LPME was detected with high performance liquid chroatography equipped with ultraviolet detector HPLC UV The effect of various parameters which affected extraction efficiency such as type of organic solvent, receiving phase, pH of receiving phase and extraction phase, extraction time and mixing speed were investigated Under optimum condition of extraction condition the pre concentration factor was obtained 158 for urine samples with an appropriate detection limit of 2 µg ml 1
کلیدواژهها
نویسندگان
Azam Ghorbani
Assistant Professor of Islamic Azad University of Saveh Department of Chemistry, Collage of Technology and Engineering, Saveh Branch, Islamic Azad University, Saveh, Iran
شیوه ارجاع
Ghorbani, Azam,1403,Application of Hollow Fiber based Liquid-phase Micro Extraction (HF-LPME) and Liquid chromatography for determination of Imipramin in water and Biological sample,6th National Conference on Novel Achievements in Materials Engineering, Chemical Engineering and Industrial safety,Esfarayen
ارائهشده در
مجموعه مقالات ششمین کنفرانس ملی دستاوردهای نوین در مهندسی مواد، مهندسی شیمی و ایمنی صنعتی14 آبان 1403 · اسفراین