چکیده مقاله
Introduction: Chemotherapy induced peripheral neuropathy CIPN is one of the most common neuropathies caused by antineoplastic agents Clinically, CIPN is a sensory neuropathy that may be accompanied by motor and autonomic changes of varying severity and duration One of the very important goals that nanotechnology pursues is the creation and production of nanoparticles that have the desired distribution of drugs in the body Therefore, the present study, with the approach of systematic review and meta analysis, investigates the effectiveness of the nanomedicine approach on reducing the adverse effects of peripheral neuropathy Materials and methods: In this study, a meta analysis search was conducted in Scopus, Web of science, Pubmed and Google Scholar search engines In the search of keywords such as nanoparticles, Chemotherapy induced peripheral neuropathy, adverse effect along with their Mesh terms, were done without time limit The search was done according to the PRISMA protocol ARRIVE checklist was used to check the quality of compliance Results: After searching, 207 articles were found Out of the 207 articles found, 46 articles were removed due to duplication, out of the remaining 161 articles, 148 articles were removed due to irrelevance and 7 articles were removed due to lack of access to the full text of the article, so finally 6 studies were included in the meta analysis process Conclusion: Treatment with drug delivery systems based on nanotechnology causes targeted drug delivery and controlled drug release Also, the adverse effects of peripheral neuropathy caused by chemotherapy drugs can be reduced by using nanosystems
کلیدواژهها
نویسندگان
Ahmad Fatahi-Vanani
Student Research Committee, Shahrekord University of Medical Sciences, Shahrekord, Iran
Pegah Khosravian
Medical Plants Research Center, Institute of Basic Health Sciences, Shahrekord University of Medical Sciences, Shahrekord, Iran
شیوه ارجاع
Fatahi-Vanani, Ahmad and Khosravian, Pegah,1401,Effectiveness of the nanomedicine approach on reducing the adverse effects of Chemotherapy-induced peripheral neuropathy (CIPN): A systematic review and meta-analysis,International Conference on Leading Research in Nanotechnology Students,Tehran
ارائهشده در
مجموعه مقالات اولین کنفرانس بین المللی تحقیقات پیشرو دانشجویان نانو فناوری30 آبان 1401 · تهران