چکیده مقاله
A simple, selective, linear, precise and accurate HPLC method was developed and validated for assay of Carvedilol in API and pharmaceutical dosage forms Isocratic elution at a flow rate of 1 0mL/min was employed on L1, 150 X 4 6, 5μ; Column, Column temperature 55 °C Run time: 60 min Injection size: 10μL mobile phase consisting of Potassium dihydrogen phosphate, dipotassium hydrogen phosphate and Acetonitrile in the ratio 50: 50 v/v adjusted pH 3 0 with dilute phosphoric acid solution The ultraviolet detection wavelength was at 240 nm The method was validated for Linearity, Precision, Accuracy, Ruggedness and Robustness as per ICH Guidelines The LOD and LOQ have also been established and found to be 0 8346µg/mL and 2 5292 µg/mL The validated method can be successfully applied for the estimation of Carvedilol in pharmaceutical dosage forms
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شیوه ارجاع
در صورتی که می خواهید در اثر پژوهشی خود به این مقاله ارجاع دهید، به سادگی می توانید از عبارت زیر در بخش منابع و مراجع استفاده نمایید: Khajeh Dehaghani, Mostafa,1404,Development and validation of HPLC method for determination of Carvedilol in API and pharmaceutical dosage forms,Fourth International Conference for Iranian Hygienics and Health Sciences Students,Tehran,https://civilica.com/doc/2636158
ارائهشده در
مجموعه مقالات چهارمین کنفرانس بین المللی دانشجویان بهداشت و علوم سلامت ایران30 بهمن 1404 · تهران