چکیده مقاله
Due to the importance of increasing diseases caused by Mycobacterium tuberculosis worldwide, we have conducted a study to evaluate the genome of these diseases in our region The aim of this study is to investigate the genomic TB19c in Mycobacterium tuberculosis This descriptive study was conducted on 9,000 samples isolated from patients with pulmonary tuberculosis symptoms between 1390 and 1402 at the Mycobacteriology Research Center To identify mycobacterium species, a bp190 fragment of IS6110 gene was first amplified using Tb2 and Tb1 primers The samples that had a negative PCR result based on IS6110 were analyzed in order to investigate non tuberculous mycobacteria using hsp65 gene by PCR RFLP method From all 9000 samples, 124 NTM strains were identified, which were very significant in terms of TB19c genome The average age of the studied NTM patients was 57±18 9 years with an age range of 7 88 years , and the majority of these patients 55 6% were male In this study, we observed a high prevalence of mycobacteria among patients Due to the fact that the treatment protocol based on TB19c genome examination is different in the case of mycobacteria, so the diagnosis of these species as soon as possible will be of significant importance for doctors
کلیدواژهها
نویسندگان
Jafar Aghajani
Mycobacteriology Research Center MRC , National Research Institute of Tuberculosis and Lung Disease NRITLD , Shahid Beheshti University of Medical Sciences, Tehran, Iran
Parissa Farmia
Mycobacteriology Research Center MRC , National Research Institute of Tuberculosis and Lung Disease NRITLD , Shahid Beheshti University of Medical Sciences, Tehran, Iran
Saman Ayoubi
Mycobacteriology Research Center MRC , National Research Institute of Tuberculosis and Lung Disease NRITLD , Shahid Beheshti University of Medical Sciences, Tehran, Iran
Poopak Farmia
Mycobacteriology Research Center MRC , National Research Institute of Tuberculosis and Lung Disease NRITLD , Shahid Beheshti University of Medical Sciences, Tehran, Iran Department of Biotechnology, School of Advanced Technology in Medicine, Shahid Beh
Jalaledin Ghanavi
Mycobacteriology Research Center MRC , National Research Institute of Tuberculosis and Lung Disease NRITLD , Shahid Beheshti University of Medical Sciences, Tehran, Iran
Ali Akbar Velayati
Mycobacteriology Research Center MRC , National Research Institute of Tuberculosis and Lung Disease NRITLD , Shahid Beheshti University of Medical Sciences, Tehran, Iran
شیوه ارجاع
Aghajani, Jafar and Farmia, Parissa and Ayoubi, Saman and Farmia, Poopak and Ghanavi, Jalaledin and Velayati, Ali Akbar,1402,Genomic investigation of TB19c in Mycobacterium tuberculosis,The first international conference of health and health sciences students of Iran,Tehran
ارائهشده در
مجموعه مقالات اولین کنفرانس بین المللی دانشجویان بهداشت و علوم سلامت ایران31 اردیبهشت 1402 · تهران