چکیده مقاله
Purpose: The purpose of the present study was to systematically review infertility problems on patients with breast cancer, conduct a meta analysis, if possible, and to emphasize the main points of proper treatment, including some available choices to keep fertility Methods: 108 titles and abstracts were found from databases of MEDLINE, EMBASE, Scopus, Cochrane, and web of science data Nine articles have been chosen for systematic review after duplicate elimination and selection of eligible ones were included with criteria such as young female breast cancer with concerns related to fertility, ovarian failure or fertility related symptoms, and upper 50 years’ age limitation Results: Nine studies were included in this systematic review, from which seven studies 2014 2018, n = 1697 women , by choosing newer studies on single populations went under meta analyzed It was revealed that the prevalence of infertility in women with breast cancer with a range of 48 5% 95% CI: minimum of 25 5% and maximum of72 2% was significant This would be an important issue for young breast cancer survivors, whether going for fertility preservation or not Conclusion: Young breast cancer survivors should be awarded the issues related to fertility and be prepared to discuss options for fertility preservation Due to the limited studies, the results should be going under further validations by vaster heterogeneity and in cohort studies with short term parameters, biomarkers related to ovarian function evaluating the infertility problems; and there would be a demand for further studies on better therapies shortened the consequences on the fertility
کلیدواژهها
نویسندگان
Seyyed Mojtaba Ghorani
School of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
شیوه ارجاع
Ghorani, Seyyed Mojtaba,1399,Infertility Problems in Young Women with Breast Cancer Undergoing Chemotherapy: A Systematic Review and Meta-analysis,3rd International Conference on New Findings in Midwifery, Obstetrics, Gynecology and Infertility
ارائهشده در
مجموعه مقالات سومین کنفرانس بین المللی یافته های نو در مامایی، زنان، زایمان و نازایی2 اسفند 1399