چکیده مقاله
Despite major advances in surgery, chemotherapy, and surveillance strategies, colorectal cancer CRC recurrence remains a critical clinical challenge Early detection of relapse significantly improves the chances of successful intervention; however, currently available biomarkers such as carcinoembryonic antigen CEA lack sufficient sensitivity and specificity 1,13 In recent years, long non coding RNAs lncRNAs have emerged as key regulators in cancer biology 2,3 Growing evidence supports their role in tumor progression, metastasis, and therapy resistance 3,14 Importantly, several lncRNAs have shown potential as minimally invasive biomarkers for detecting CRC recurrence This narrative review summarizes current evidence regarding the biological functions of lncRNAs in CRC and evaluates their emerging role in the early detection of disease relapse
کلیدواژهها
نویسندگان
Seyed Kazm Mirinezhad
Liver and Gastrointestinal Disease Research Center Tabriz University of Medical Sciences: Tabriz, Iran
شیوه ارجاع
Mirinezhad, Seyed Kazm,1404,Long Non-Coding RNAs in the Early Detection of Colorectal Cancer Recurrence: A Narrative Review,18th International Conference on New Findings in Midwifery, Women, Maternity and Infertility
ارائهشده در
مجموعه مقالات هجدهمین کنفرانس بین المللی یافته های نو در مامایی، زنان، زایمان و نازایی26 اسفند 1404