چکیده مقاله
cervical cancer is the second fatal and common cancer among female Iranian population Growth and metastasis of the tumor depends on a various factors playing roles in angiogenesis Vascular endothelial growth factor VEGF is one the key factors contributing to angiogenesis The study investigated the effects of rosuvastatin on VEGF genes expression in Hela cells After culturing and preparing the cells, cells were treated with rosuvastatin in 5μM, 10μM, 25μM, 50μM, 100μM in new media MTT tests and real time PCR were utilized to assay cells proliferation and gene expression, respectively The results demonstrated that VEGF gene expression was inhibited whit higher concentration of rosuvastatin
کلیدواژهها
نویسندگان
Mohaddeseh Rahbaran
Animal Biotechnology Department, National Institute of Genetic Engineering and Biotechnology NIGEB , Tehran, Iran
شیوه ارجاع
Rahbaran, Mohaddeseh,1399,Study of the Rosuvastatin effects on VEGF expression in Hela cells,3rd International Conference on New Findings in Midwifery, Obstetrics, Gynecology and Infertility
ارائهشده در
مجموعه مقالات سومین کنفرانس بین المللی یافته های نو در مامایی، زنان، زایمان و نازایی2 اسفند 1399