چکیده مقاله
Introduction: Mastalgia or breast pain is one of the most common breast disorders in women Painful mastalgia can affect a woman’s quality of life as well as her sexual, social and physical activities Centchroman or ormeloxifene, is relatively new agent that is used for the treatment of gynecological disorders such as mastalgia Objectives: To investigate the effect of Centchroman on mastalgia and its side effects based on a systematic review of the literature Methods: The databases were searched in March 2018 Quality assessment of randomized clinical trials was conducted using the The Cochrane Collaboration's tool for assessing risk of bias in randomized trials The quality of non randomised studies, was assessed using the Cochrane Risk of Bias Assessment Tool: for Non Randomized Studies of Interventions ACROBAT NRSI Results: Thirteen studies were included in the study Among them, 12 studies indicated the significant effect of Centchroman on the reduction of breast pain 3 months after the intervention Six studies indicated the effectiveness of Centchroman at the end of 6th month None of the papers reported any serious side effects of Centchroman Conclusion: Although the results of this study showed that Centchroman can be useful in relieving mastalgia, Since the meta analysis was not conducted and the quality of included studies was low, there is no sufficient evidence for judging the effect of Centchroman on mastalgia Therefore, conducting well designed randomized controlled clinical trials that compare the effect of Centchroman with the effect of placebo or other medicines on mastalgia treatment is strongly recommended
کلیدواژهها
نویسندگان
Nafiseh Ghassab-Abdollahi
Students’ Research Committee, Department of Health Education & Promotion, School of Health Tabriz University of Medical Sciences, Tabriz, Iran
Mojgan Mirghafourvand
Social Determinants of Health Research Center , Tabriz University of Medical Sciences, Tabriz, Iran Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran
Shirin Osouli Tabrizi
Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran
شیوه ارجاع
Ghassab-Abdollahi, Nafiseh and Mirghafourvand, Mojgan and Osouli Tabrizi, Shirin,1399,The effect of centchroman on mastalgia: a systematic review,3rd International Conference on New Findings in Midwifery, Obstetrics, Gynecology and Infertility
ارائهشده در
مجموعه مقالات سومین کنفرانس بین المللی یافته های نو در مامایی، زنان، زایمان و نازایی2 اسفند 1399