چکیده مقاله
Background: Pumpkin seed extract can be a good alternative to hormone replacement therapy since it is rich in phytoestrogens The present research aimed to investigate the effect of hydroalcoholic extract of pumpkin seeds on the regulation of estrogen and progesterone hormones and Kidney Markers Methods: This experimental study was performed on 64 Wistar female rats including 32 adults and 32 immature rats The adult rats were randomly divided into three experimental and one control groups n=8 per group Moreover, the immature rats were allocated to groups in a similar manner The experimental groups 1, 2, and 3 received a hydro alcoholic extract of pumpkin seedin doses of 20, 50,100 mg/kg, respectively, via intraperitoneal injection for 21 consecutive days For the purposes of the study, blood samples were taken one day after the last injection to determine the serum levels of female hormones as well as renal The ovarie and kidneys of the rats were also separated for histological tests Results: Based on the results, significant increases were observed in the bodyweight of all immature rats; estrogen levels in the adult experimental group 3 and immature experimental groups2 and 3; progesterone and creatinine levels in the immature experimental group 3; uric acid UA and the renal diameter in the immature experimental groups 1 and 2; follicle stimulating hormone in the adult experimental group 3 and the immature experimental groups 1 and 2; luteinizing hormone and Graafian follicles in the adult experimental group 3; and atretic follicles in the immature experimental group 1 and 3 P
کلیدواژهها
نویسندگان
Samaneh Motamed Jahromi
Expert in traditional medicine, Molecular Medicine Research Center, Hormozgan Health Institute, Hormozgan University of Medical Sciences,Bandar Abbas, Iran
Sadegh Niami Jahromi
Technical Expert in charge of Electricity Department, Shipping Reservoir Unit, Qeshm Shipping, Bandar Abbas, Iran
شیوه ارجاع
Motamed Jahromi, Samaneh and Niami Jahromi, Sadegh,1399,The effect of hydro-alcoholic extract of pumpkin seeds on the regulation of estrogen and progesterone hormones and Kidney Markers,3rd International Conference on New Findings in Midwifery, Obstetrics, Gynecology and Infertility
ارائهشده در
مجموعه مقالات سومین کنفرانس بین المللی یافته های نو در مامایی، زنان، زایمان و نازایی2 اسفند 1399