چکیده مقاله
In the present work, highly efficient method for the synthesis of 3 substituted 4 arylmethylidene isoxazol 5 4H one heterocyclic compounds by the three component reaction between substituted benzaldehydes, β keto esters, and hydroxylamine hydrochloride under the influence by iodine as commercially available, inexpensive, and easy to handle catalyst has been described The benefits of this method are good yields, relatively shorter reaction times, simplicity of implementation, using water as the solvent, and respect of the environment
کلیدواژهها
Aqueous media Iodine 3-Substituted-4-arylmethylidene-isoxazol-5(4H)-one Three-component Greensynthesis. 3 Substituted 4 arylmethylidene isoxazol 5 4H one Three component Greensynthesis
نویسندگان
Hanieh Ostadzadeha
School of Chemistry, Damghan University,
Hamzeh Kiyania
School of Chemistry, Damghan University,
شیوه ارجاع
Ostadzadeha, Hanieh and Kiyania, Hamzeh,1397,One-pot synthesis of isoxazole-5(4H)-ones via three-component condensation of β-keto esters, hydroxylamine hydrochloride, and substituted benzaldehydes in the presence of iodine in water,Fourth National Conference on Materials Engineering, Chemical Engineering and Industrial Safety,Esfarayen
ارائهشده در
مجموعه مقالات چهارمین کنفرانس ملی مهندسی مواد، مهندسی شیمی و ایمنی صنعتی18 مهر 1397 · اسفراین