چکیده مقاله
Glioblastomas are the most common and among the deadliest brain tumors. Accurate multiphysics modeling of the tumor is crucial and could aid the experts in choosing the best therapeutic strategy. This study aims to examine the different approaches and requirements for modeling the growth of the tumor and demonstrate the differences in short-term and long-term modeling. To validate the accuracy of our results, we used data from two patients diagnosed with GBM. The performance and accuracy of our models were evaluated by comparing the predicted results with actual MRI scans from these patients. Our primary results showed that although all models could illustrate tumor growth in different parts of the brain, the best results were obtained using the patients' MRI series, which resulted in the lowest modeling errors for both patients. Patients who underwent full resection were better modeled, with an error rate lower than 10 percent. For short-term comparisons, using T2 MRIs was more accurate than using T1Gd MRIs.
کلیدواژهها
نویسندگان
Navid Moshtaghi Kashanian
Division of Biomechanics, Department of Biomedical Engineering, Sahand University of Technology, Tabriz, Iran,
Hanieh Niroomand-Oscuii
Division of Biomechanics, Department of Biomedical Engineering, Sahand University of Technology, Tabriz, Iran,
Shahriar Dabiri
Pathology and Stem Cell Research Center, Kerman University of Medical Sciences, Kerman, Iran,
Narges Meghdadi
Division of Biomechanics, Department of Biomedical Engineering, Sahand University of Technology, Tabriz, Iran,
Masoud Eslami
Neurosurgery department, Kerman University of Medical Sciences, Kerman, Iran,
Simin Soltani Nejad
Department of Radiation Oncology, Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran,
شیوه ارجاع
Moshtaghi Kashanian, Navid and Niroomand-Oscuii, Hanieh and Dabiri, Shahriar and Meghdadi, Narges and Eslami, Masoud and Soltani Nejad, Simin,1403,The Effect of Parameter Estimation Methods in Modeling Glioblastoma Growth Prediction,1st International Congress on Cancer Prevention,Zanjan
ارائهشده در
مجموعه مقالات اولین کنگره بین المللی پیشگیری از سرطان28 شهریور 1403 · زنجان