چکیده مقاله
Background: Infertility, affecting up to 15% of reproductive aged couples globally, is a significant physical and psychological stressor, often leading to anxiety, depression, and reduced quality of life While assisted reproductive technologies ART are standard, nurse led integrative interventions combining mind body practices and lifestyle modifications are increasingly explored as adjunct therapies This systematic review and meta analysis aimed to rigorously evaluate the impact of these nurse delivered integrative interventions on clinical pregnancy rates, live birth rates, and patient reported psychological outcomes in individuals undergoing infertility treatment Methods: A systematic literature search was conducted across PubMed, Scopus, Web of Science, and the Cochrane Central Register of Controlled Trials CENTRAL from inception to July 2025 The search strategy utilized a combination of Medical Subject Headings MeSH and free text terms related to infertility, nursing, mind body, lifestyle, and randomized controlled trial Included studies randomized controlled trials RCTs or quasi experimental studies of nurse delivered interventions integrating mind body techniques e g , meditation, yoga and/or lifestyle modifications e g , diet, exercise Two independent reviewers screened articles, extracted data, and assessed the risk of bias using the Cochrane Risk of Bias RoB 2 0 tool Meta analyses employed random effects models DerSimonian Laird method to calculate pooled relative risks RR for binary outcomes pregnancy, live birth and standardized mean differences SMD for continuous psychological outcomes anxiety, stress Heterogeneity was assessed using the I 2 statistic, and publication bias was explored with Egger's and Begg's tests Results: A total of 17 studies, encompassing 2,150 participants, met the inclusion criteria The pooled results indicated that nurse led integrative interventions significantly improved clinical pregnancy rates compared to usual care or waiting list controls RR = 1 31, 95% CI: 1 10–1 56, p = 0 002 While an increase in live birth rates was observed, it did not reach statistical significance RR = 1 20, 95% CI: 0 95–1 51, p = 0 13 Importantly, these interventions were highly effective in enhancing psychological well being, showing a large, statistically significant reduction in self reported stress and anxiety SMD = 0 44, 95% CI: 0 22–0 66, p < 0 001 Subgroup analysis suggested that interventions combining both mind body training and comprehensive lifestyle education had the largest effect size Publication bias was low across all primary outcomes Egger's test, p > 0 05 Conclusion: Nurse led integrative mind body and lifestyle interventions are a clinically impactful and evidence based adjunct therapy in infertility care They demonstrate significant efficacy in improving both reproductive outcomes, specifically clinical pregnancy rates, and crucial patient reported psychosocial outcomes These findings strongly support the integration of these holistic nursing programs into standard infertility treatment pathways to improve patient care and treatment success
کلیدواژهها
نویسندگان
Sana Mahdian Rizi
Students Research Committee, Neyshabur University of Medical Sciences, Neyshabur, Iran
شیوه ارجاع
Mahdian Rizi, Sana,1404,Integrative Mind-Body and Lifestyle Nursing Interventions for Infertility: A Systematic Review and Meta-Analysis of Clinical Efficacy and Patient-Reported Outcomes,17th International Conference on New Findings in Midwifery, Women, Maternity and Infertility
ارائهشده در
مجموعه مقالات هفدهمین کنفرانس بین المللی یافته های نو در مامایی،زنان ،زایمان و نازایی7 آذر 1404