چکیده مقاله
Duphaston is used as an alternative to gonadotropin releasing hormone GnRH antagonists for suppressing premature luteinizing hormone LH surges This study aimed to compare the efficacy of Duphaston protocols with that of Cetrotide in suppressing the LH surge In this retrospective cross sectional study, 669 infertile women aged 25–40 years were administered recombinant follicle stimulating rFSH hormone from the third day of their menstrual cycle After the follicular diameter reached–13 14 mm, Cetrotide was prescribed orally to the control subjects, also case subjects took Duphaston orally The retrieved oocytes were fertilized by an intracytoplasmic sperm injection ICSI The levels of FSH, LH, and estradiol did not differ significantly between the groups p>0 05 However, the findings indicated that Duphaston led to greater oocyte retrieval than Cetrotide p=0 006 However, the number of mature oocytes and viable embryos in the case subjects did not reach a significant difference compared to that in the control subjects p>0 05 The number of good quality embryos stage1 was significantly higher in the case subjects p=0 04 In addition, there is no significant difference in the Chemical ,Clinical pregnancy, Implantation rate, and Miscarriage rate between both groups P>0 05 Overall, Duphaston could be utilized as a suitable medication rather than a GnRH antagonist in women subjected to controlled ovarian hyperstimulation
کلیدواژهها
نویسندگان
Leila Naserpoor
Department of Reproductive Biology, Academic Center for Education, Culture, and Research ACECR , Qom Branch, Qom, Iran
Katayon Berjis
Infertility treatment center, Academic Center for Education, Culture, and Research ACECR , Qom Branch, Qom, Iran
Sanaz Soleymani Moud
Infertility treatment center, Academic Center for Education, Culture, and Research ACECR , Qom Branch, Qom, Iran Midwifery Ward, Infertility Treatment Center, Academic Center for Education, Culture, and Research ACECR , Qom Branch, Qom, Iran
Rahil Jannatifar
Department of Reproductive Biology, Academic Center for Education, Culture, and Research ACECR , Qom Branch, Qom, Iran Infertility treatment center, Academic Center for Education, Culture, and Research ACECR , Qom Branch, Qom, Iran
شیوه ارجاع
Naserpoor, Leila and Berjis, Katayon and Soleymani Moud, Sanaz and Jannatifar, Rahil,1402,Duphaston as a suitable medication for women taking intracytoplasmic sperm injection to treat infertility13,The 15th International Conference on Health, Treatment and Health Promotion
ارائهشده در
مجموعه مقالات پانزدهمین کنفرانس بین المللی بهداشت، درمان و ارتقای سلامت1 دی 1402