چکیده مقاله
Generative artificial intelligence AI entered mainstream discourse with the release of ChatGPT, yet AI and machine learning ML have long been embedded in pharmaceutical research and development R&D These technologies now span nearly every phase of biopharmaceutical R&D, including target identification, compound optimization, clinical trial design, regulatory documentation, supply chain logistics, and post marketing surveillance Although precision medicine is still often described as a “futuristic” paradigm in peer reviewed literature, the integration of AI is rapidly steering drug discovery toward individualized, patient centric models Generative AI, while dominant in consumer platforms, represents only one subset of a broader computational ecosystem The pharmaceutical industry has relied on predictive modeling for years, and recent advances in ML have enabled researchers to stratify patient populations, forecast mechanisms of action, predict differential drug responses, including toxicity, and refine dosing strategies These innovations are accelerating the shift from generalized therapeutics to precision medicine tailored to molecular, genetic, and phenotypic profiles Moreover, the convergence of AI with multi omics data, real world evidence, and digital biomarkers is enhancing the resolution of patient stratification and therapeutic targeting As AI systems become more interpretable and data integration improves, their role in clinical decision making and translational research is expected to expand, bridging the gap between bench and bedside Ultimately, AI driven precision medicine holds the potential to reduce drug development timelines, lower costs, and improve long term patient outcomes through more effective and safer therapies This article explores accelerating the precision medicine path in drug discovery through artificial intelligence
کلیدواژهها
نویسندگان
Amirreza Talebi
Medical Doctor, Resident of Radiology, Tehran University of Medical Sciences, Tehran, Iran
Pouyan Asadi
Medical Cellular and Molecular Research Center, Golestan University of Medical Sciences, Gorgan, Iran
Ali Shekarian
Department of Computer and Data Sciences, Faculty of Mathematical Sciences, Shahid Beheshti University, Tehran, Iran
Sobhan Salari
Master student in Geopolitics at Dafoos University, Tehran, Iran
Rabee Movagharnia
Department of Genetics and Biotechnology, School of Biological Sciences, Varamin Pishva Branch, Islamic Azad University, Varamin, Iran
شیوه ارجاع
Talebi, Amirreza and Asadi, Pouyan and Shekarian, Ali and Salari, Sobhan and Movagharnia, Rabee,1404,Accelerating The Path To Precision Medicine in Drug Discovery through AI,8th International conference on Health, Educational Sciences and psychology
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مجموعه مقالات هشتمین کنفرانس بین المللی سلامت، علوم تربیتی و روانشناسی30 آبان 1404