چکیده مقاله
The third novel coronavirus to emerge, in 2019, is called COVID 19 It chiefly affects the respiratory system; However, there are reports of coronaviruses causing cognitive and neurological manifestations The aim of this study was to systematic review the evidence regarding cognitive and neurological effects of the COVID 19, as well as its direct and indirect effects We conducted a systematic literature search from December 2019 to 2021 January The articles were searched in the databases including PubMed, Scopus, Web of sciences WOS and Google Scholar, the Scientific Information Database SID as a national database They included articles with cases of COVID 19 where neurological involvement was evident The total of 47 articles were selected According to the inclusion criteria, 39 articles were regarded as appropriate There were 27 review articles, 7 original studies and 3 case reports, from January 2020 to December 2020 Fatigue, headache, and smell/taste disorders and anosmia were common neurological manifestations and also cerebrovascular disorders such as ischemic stroke, encephalopathies, post infectious immune mediated complications such as Guillain Barre syndrome and acute disseminated encephalomyelitis and seizures were reported in patient with COVID 19 In experimental studies, IL 6, TNFα and IL 1β cytokines were introduced as key elements for etiology of COVID 19 induced long term cognitive impairments The review suggests that although more articles have reported cognitive and neurological effects; However, many items remain unclear and ambiguous So, there is a need to diagnose and investigation their biological background of these manifestations at the earliest to limit long term sequelae
کلیدواژهها
نویسندگان
شیوه ارجاع
Nsirazdeh, Nafiseh and Farrokhi, Mehdi,1399,Cognitive and neurological effects of the COVID-19, An updated systematic reviews,5th International Conference on Health and Health Promotion
ارائهشده در
مجموعه مقالات پنجمین کنفرانس بین المللی بهداشت،درمان و ارتقای سلامت20 اسفند 1399