چکیده مقاله
Introduction: Changes in plasma adiponectin, leptin, and inflammatory parameters in type 2 diabetes are due to obesity and directly related to diabetes This study aimed to investigate the effect of exercise training E T on the ratio of adiponectin to leptin and C reactive protein CRP in type 2 diabetic rats Materials & Methods: In this experimental study, 24 Wistar rats with a mean weight of 211±32 were randomly assigned to healthy control, diabetic control, and diabetic exercise training groups The diabetic training group received ten weeks of E T following the induction of diabetes During the experimental period, blood samples were collected to evaluate biochemical parameters Data were analyzed using a one way analysis of variance at the significant level of P≤0 05 Findings: The induction of diabetes resulted in a significant decrease in adiponectin P =0 001 and leptin P=0 001 and an increase in C reactive protein P=0 001 in the diabetic control group compared to the healthy control group Became of E T resulted in a decrease in blood glucose P=0 121 , C reactive protein P=0 045 , and an increase in serum leptin levels P=0 021 , adiponectin P=0 32 In the E T group compared to the diabetic control group Conclusions: It seems exercise training E T improves inflammation C reactive protein in type 2 diabetic rats by altering adiponectin and leptin serum levels In the present study, eight weeks of E T group training led to an increase in the adiponectin to leptin ratio and reduced C reactive protein
کلیدواژهها
نویسندگان
Mohammad Parastesh
Department of Sports Physiology, Faculty of Sports Sciences, Arak University, Arak, Iran Research Institute of Applied Studies of Sports Sciences, Arak University, Arak, Iran
Hamidreza Khaluonejad
M S in Exercise Physiology, Department of Exercise Physiology, Arak University, Arak, Iran Department of Exercise Physiology, Faculty of Sport Sciences, Arak University, Arak, IranCorresponding author
شیوه ارجاع
Parastesh, Mohammad and Khaluonejad, Hamidreza,1402,Effects of exercise training on adiponectin, leptin, and inflammatory markers in diabetic rat,16th International Conference on Health, Treatment and Health Promotion
ارائهشده در
مجموعه مقالات شانزدهمین کنفرانس بین المللی بهداشت، درمان و ارتقای سلامت27 بهمن 1402