چکیده مقاله
Background and purpose: this study aimed to investigate the effect of resistance training RT on oxidative stress and total antioxidant capacity in rats treated with cisplatin Materials and methods: In this experimental study, 21 Sprague Dawley rat models were randomly divided into three groups: control n=7 , control cisplatin n=7 , and cisplatin with RT n=7 In cisplatin groups, 10mg/kg cisplatin was injected intraperitoneally The training groups also performed the training for ten weeks Twenty four hours after the last training session, the blood serum of rats was collected to examine the desired variables Data were analyzed using one way analysis of variance at the significant level of P≤0 05 Results: In this study, cisplatin injection caused a significant increase in malondialdehyde MDA P=0 001 , a substantial decrease in total antioxidant capacity TAC P=0 001 , and a considerable reduction in catalase CAT in the control group Compared to cisplatin control Malondialdehyde MDA was also significantly reduced in the cisplatin group with RT P=0 001 compared to the control group In addition, no significant difference was observed in total antioxidant TAC in the cisplatin group with RT P=0 227 compared to a healthy control group Also, catalase CAT in the cisplatin group with RT P=0 404 was not significantly different from the control group Conclusion: It seems that exercise with different intensities can effectively reduce the oxidative stress conditions caused by cisplatin in rats
کلیدواژهها
نویسندگان
Mohammad Parastesh
Department of Sports Physiology, Faculty of Sports Sciences, Arak University, Arak, Iran Research Institute of Applied Studies of Sports Sciences, Arak University, Arak, Iran
Hamidreza Khaluonejad
M S in Exercise Physiology, Department of Exercise Physiology, Arak University, Arak, Iran Corresponding Author, Department of Exercise Physiology, Faculty of Sports Sciences, Arak University, Arak, Iran
شیوه ارجاع
Parastesh, Mohammad and Khaluonejad, Hamidreza,1402,Protective role of resistance training against cisplatin-induced oxidative stress in rats,16th International Conference on Health, Treatment and Health Promotion
ارائهشده در
مجموعه مقالات شانزدهمین کنفرانس بین المللی بهداشت، درمان و ارتقای سلامت27 بهمن 1402