چکیده مقاله
Background: Female breast and gynecological cancers FeBGCs are the most prevalent health concerns and the leading causes of cancer related deaths among women However, there is a lack of comprehensive studies examining the burden of FeBGCs in Asia This study aims to assess the temporal burden of major FeBGCs in Asia from 1990 to 2021 Methods: The estimates of incidence, death, disability adjusted life years DALYs and risk factors of breast cancer BC , cervical cancer CC , ovarian cancer OC , and uterine cancer UC in 48 Asian countries and global were retrieved from the Global Burden of Disease GBD 2021 study from 1990 to 2021 Epidemiological characteristics were analyzed based on age, year, location, risk factors and socio demographic index SDI Results: In 2021, in Asia, BC, CC, OC, and UC contributed to 10,335,176 95% CI: 9,280,423~11,485,400 , 5,318,838 95% CI: 4,733,230~5,916,377 , 2,568,854 95% CI: 2,233,137~2,992,341 , and 1,076,127 95% CI: 889,739~1,303,328 DALYs, with corresponding increases of 1 59 fold, 0 31 fold, 1 48 fold, and 0 72 fold since 1990 The highest DALY counts for BC occurred at ages 50 54, while CC, OC, and UC DALY counts peaked at ages 55 59 before declining in older groups In 2021, a diet high in red meat was the leading contributor to BC DALY in Asia 10 6% , though its impact slightly declined compared to 1990 High BMI emerged as a significant risk factor for BC, OC, and UC, with its impact on mortality and DALYs nearly doubling in Asia and rising significantly globally from 1990 BC incidence shows a positive correlation with higher SDI levels, while mortality and DALYs exhibit a weak, fluctuating negative association with SDI CC consistently demonstrates a significant negative association with SDI for all indicators Conclusions: This study demonstrates BC and OC have seen a significant rise in Asia, especially in Western Asia, while global trends show improvements in mortality and DALYs Addressing these disparities will require region specific strategies in cancer prevention and tailored interventions Keywords: Cancer Burden, Asia, Breast Cancer, Cervical Cancer, Ovarian Cancer, Uterine Cancer, Gynecological Cancer, Risk Factors
کلیدواژهها
نویسندگان
شیوه ارجاع
Gheisaria, Zohreh and Jiang, Donglin and Ye, Hua,1404,Epidemiological burden of Female Breast and Gynecological Cancers in Asian Countries from 1990 to 2021: An Analysis for Global Burden of Disease Study 2021,19th International Conference on Health, Treatment and Health Promotion
ارائهشده در
مجموعه مقالات نوزدهمین کنفرانس بین المللی بهداشت، درمان و ارتقای سلامت20 فروردین 1404