چکیده مقاله
Management of tuberculosis in pediatrics The standard regimen consists of: The intensive phase with 3 4 drugs isoniazid, rifampin also known as rifampicin outside the United States , and pyrazinamide, with or without ethambutol for 2 months The continuation phase with isoniazid plus rifampin for 2 10 months The recommended duration varies by age and clinical presentation Give continuation phase regimen for 2 months in children aged 3 months to 16 years with nonsevere pulmonary TB or tuberculous peripheral lymphadenitis, without HIV infection or severe acute malnutrition or history of TB treatment in previous 2 years Give continuation phase regimen for 4 months for most other forms of TB Give continuation phase regimen for 10 months for tuberculous meningitis or osteoarticular tuberculosis For treatment of drug resistant TB: Treatment options are determined by the resistance pattern of the causal organism in patients with multidrug resistant TB MDR TB or extensively drug resistant TB XDR TB MDR and XDR TB should be managed in consultation with an infectious disease/tuberculosis expert For children and adolescents aged 3 months to 16 years: The intensive phase consists of isoniazid, rifampin, pyrazinamide, and ethambutol for 2 months The continuation phase consists of isoniazid plus rifampin for 4 months If tuberculosis meningitis is presumed or confirmed: The preferred treatment is a 12 month standard dose treatment regimen, consisting of and intensive phase with isoniazid, rifampin, pyrazinamide, ethambutol for 2 months and a continuation phase with isoniazid plus rifampin for 10 months For all other forms of extrapulmonary TB excluding peripheral lymph node TB, tuberculosis meningitis, and osteoarticular TB , use a 6 month treatment regimen consisting of an intensive phase with isoniazid, rifampin, and pyrazinamide, with or without ethambutol for 2 months and a continuation phase with isoniazid plus rifampin for 4 months
نویسندگان
Mohsen Mohammadi
Non Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran
شیوه ارجاع
Mohammadi, Mohsen,1404,Infectious Management of TB in pediatrics,37th International Congress on Pediatrics,Tehran
ارائهشده در
مجموعه مقالات سی و هفتمین کنگره بیماری های کودکان17 مهر 1404 · تهران