چکیده مقاله
Our aim in this study is to analyze the flavonoids catechin,kaempferol, luteolin,quersetin and apigeninof Salvia fruticosa MILLER , Punica granatum L ,Juglans regia L , Matricaria chamomilla L , andinvestigating the antidiabetic effect caused by the presence of flavonoids in these plants In this study,leaves of Juglans regia L , leaves and above ground parts of Salvia fruticosa MILLER , flowers ofMatricaria chamomilla L , and peel of Punica granatum L were collected for analysis The samplesfirst dried and their ethanol extract was prepared in the form of a very fine powder with 25 ml of 80%ethanol and 5 grams of dried samples The analysis of the device was done with HPLC method andOptimal parameters for HPLC were determined before quantitative analysis Injection volume : 20microliter , Column temperature : 35 °C , The flow rate: 1 ml/min 0 01×10 6m3/s , Mobil faz A: %0 1 Formic acid Mobil faz B: MeOH: ACN: Formic acid : 9: 1: 0 1 The analysis results showedthat there is catechin in All samples but its amount is significantly higher in peel of Punica granatumL extract The highest and lowest quercetin concentrations were found respectively Salvia fruticosaMILLER , 3 0461g/l and peel of Punica granatum L 0 7029 g/l, The highest apigenin concentrationswas found in flower of Matricaria chamomilla 3 5599g/l Luteolin and kaempferol were found inleaves of Juglans regia L , respectively 1 073 g/l and 1 6265 g/L, and were not found in the rest of thesamples In the selected samples the highest total quercetin, apigenin , catechin ,kaempferol andLuteolin concentrations were 12/8580 g/l in Salvia fruticosa MILLER and lowest concentrations werefound 8 3230 g/l in Matricaria chamomilla L According to the proven effects of flavonoids in thetreatment of diabetes, it can be concluded that in these 4 samples, especially Salvia fruticosaMILLER , there are antidiabetic effects caused by these flavonoids and they can be used as diabetesmellitus and Hyperglycemia treatment in the long time
کلیدواژهها
نویسندگان
Noushin Shakouri
Phd student of Biochemistry in Faculty of veterinary medicine University of Ondokuzmayıs,Samsun,Turkey
Cevat Nisbet
Departman of Biochemistry, Faculty of veterinary medicine, University of Ondokuzmayıs, Samsun, Turkey
شیوه ارجاع
Shakouri, Noushin and Nisbet, Cevat,1402,Determination of Flavonoid Compounds in Medicinal Plants and Fruits with Antidiyabetic Properties by HPLC,The 7th International Conference on Interdisciplinary Studies in Food Industry and Nutrition Sciences of Iran,Tehran
ارائهشده در
مجموعه مقالات هفتمین همایش بین المللی مطالعات میان رشته ای در صنایع غذایی و علوم تغذیه ایران30 آبان 1402 · تهران