چکیده مقاله
Melanoma, recognized as one of the most aggressive skin cancers, continues to present significant diagnostic and therapeutic challenges Recent advancements in nanotechnology, particularly the use of gold nanoparticles AuNPs , have introduced innovative theranostic strategies that integrate imaging and therapy This review examines the physicochemical properties of AuNPs, including size, morphology, and surface functionalization, and their role in enhancing various imaging modalities, such as photoacoustic imaging, CT, MRI, fluorescence, and photothermal imaging Furthermore, it discusses the therapeutic potential of AuNPs in photothermal therapy PTT , photodynamic therapy PDT , and as radiosensitizers The article also addresses the challenges related to toxicity, targeting efficiency, and clinical translation Finally, future perspectives highlight the importance of personalized medicine, AI integration, and novel nanoparticle designs to enhance efficacy and safety in melanoma treatment Overall, AuNPs hold considerable promise as multifunctional agents for advancing the diagnosis and treatment of melanoma
کلیدواژهها
نویسندگان
Hanieh Akbari
Department of Biomedical Engineering, SR C, Islamic Azad University, Tehran, Iran
Neda Attaran Kakhki
Department of Medical Nanotechnology, SR C, Islamic Azad University, Tehran, Iran
Sepideh Mirzaei
Department of Biology, Faculty of Science, SR C, Islamic Azad University, Tehran, Iran
شیوه ارجاع
Akbari, Hanieh and Attaran Kakhki, Neda and Mirzaei, Sepideh,1404,A review on Gold Nanoparticles as Theranostic agents in imaging and treatment of Melanoma,Fourth International Conference on Leading Research of Nanotechnology Students,Tehran
ارائهشده در
مجموعه مقالات چهارمین کنفرانس بین المللی تحقیقات پیشرو دانشجویان نانو فناوری31 شهریور 1404 · تهران