چکیده مقاله
This study presents a novel colorimetric sensor utilizing the erythrosine mercury ERS Hg complex for the selective and sensitive detection of atropine The interaction between atropine and the ERS Hg complex induces distinct spectral changes in the UV Vis absorption spectrum, accompanied by a visible color transition from violet to orange The sensor demonstrates high sensitivity with a detection limit of 0 42 _x0003_95M and a linear response range up to 12 _x0003_95M Mechanistic studies, including Benesi Hildebrand analysis, confirm a 1:1 binding stoichiometry with a stability constant of 0 243 M 1 The method exhibits excellent selectivity against common ions and organic interferents, and its applicability is validated through successful atropine quantification in pharmaceutical tablets and spiked human urine samples with recovery rates of 97 102% This cost effective, rapid, and instrument free approach holds significant potential for pharmaceutical quality control and clinical diagnostics
کلیدواژهها
نویسندگان
Behnam khoddami
Department of Chemistry, Faculty of Basic Sciences, Payam Noor University, Tehran, Iran
شیوه ارجاع
khoddami, Behnam,1404,Development of a Colorimetric Sensor Based on Erythrosine-Mercury Complex for Selective Detection of Atropine,Fourth International Conference on Leading Research of Nanotechnology Students,Tehran
ارائهشده در
مجموعه مقالات چهارمین کنفرانس بین المللی تحقیقات پیشرو دانشجویان نانو فناوری31 شهریور 1404 · تهران