چکیده مقاله
This study presents a novel spectrophotometric method for the sensitive and selective detection of thiamazole methimazole using Alizarin Red S as a chromogenic reagent The interaction between thiamazole and Alizarin Red S results in the formation of a stable 1:1 complex, characterized by a distinct increase in absorbance at 520 nm and a visible color change from yellow orange to reddish purple Under optimized conditions pH 7, 35°C, 15 min reaction time , the method demonstrates excellent linearity R² = 0 998 over a concentration range of 1 8 µg/mL, with high precision and minimal interference from common pharmaceutical excipients The method was successfully applied to quantify thiamazole in commercial tablet formulations, achieving recovery rates of 98 5 101 2% and relative standard deviations below 1 5% This cost effective, rapid, and instrument friendly approach is well suited for routine quality control and pharmaceutical analysis
کلیدواژهها
نویسندگان
Behnam khoddami
Department of Chemistry, Faculty of Basic Sciences, Payam Noor University, Tehran, Iran
شیوه ارجاع
khoddami, Behnam,1404,Development of a Spectrophotometric Method for Thiamazole Detection Using Alizarin Red S,Fourth International Conference on Leading Research of Nanotechnology Students,Tehran
ارائهشده در
مجموعه مقالات چهارمین کنفرانس بین المللی تحقیقات پیشرو دانشجویان نانو فناوری31 شهریور 1404 · تهران