چکیده مقاله
Background: This study investigated the effects of high intensity interval training HIIT , nano selenium NS , and their combination on the expression of key metabolic genes GLUT4, AMPK, and AKT in breast tumor tissue of a murine model Methods: Thirty two male BALB/c mice bearing 4T1 mammary tumors were randomly assigned to four groups n = 8 each : tumor bearing control BT , tumor HIIT BT EX , tumor nano selenium BT NS , and tumor HIIT nano selenium BT EX NS HIIT was performed on a treadmill for 30 minutes/day, five days/week over four weeks Nano selenium 0 5 mg/kg was administered daily by oral gavage Real time PCR was used to quantify GLUT4, AMPK, and AKT mRNA expression in tumor tissues Results: Both HIIT and nano selenium significantly reduced GLUT4 expression compared to controls p
کلیدواژهها
نویسندگان
Samira Neshati
Department of Physical Education and Sport Sciences, SR C , Islamic Azad university, Tehran, Iran
Mandana Gholami
Department of Physical Education and Sport Sciences, SR C , Islamic Azad university, Tehran, Iran
Hossein Shirvani
Exercise Physiology Research Center, life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
Farshad Ghazalian
Exercise Physiology Research Center, life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
Hossein Abednatanzi
Exercise Physiology Research Center, life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
شیوه ارجاع
Neshati, Samira and Gholami, Mandana and Shirvani, Hossein and Ghazalian, Farshad and Abednatanzi, Hossein,1405,Combined High-Intensity Interval Training and Nano-Selenium Modulate GLUT4, AMPK, and AKT Gene Expression in a Murine Breast Cancer Model,Tenth international Conference on Sports Science, Physical Education and Social Health,Tehran
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