چکیده مقاله
Traumatic brain injury TBI is a critical concern in elderly populations, particularly in individuals with Alzheimer's disease AD , where brain atrophy may influence injury outcomes This study employed finite element analysis to investigate the effects of rotational head impacts on two brain models: one representing healthy aging with a 0 5% annual atrophy and another representing AD with a 4% annual atrophy The peak normal stress in the frontal region was slightly lower in the AD model 0 24803 MPa compared to the healthy aging model 0 25025 MPa , likely due to increased cerebrospinal fluid thickness However, the first principal strain at the end of the simulation was higher in the AD model 0 1222 than in the healthy aging model 0 1171 , indicating greater tissue deformation These findings highlight that while atrophy related CSF increases can reduce stress, they may also enhance relative motion between brain and skull, potentially increasing the risk of injury Future studies should incorporate patient specific atrophy patterns and various impact scenarios to better understand brain vulnerability in neurodegenerative conditions
کلیدواژهها
نویسندگان
Sajad Azizi
Department of Biomedical Engineering, Faculty of Medical Sciences and Technologies, Science and Research Branch, Islamic Azad University, Tehran, Iran
شیوه ارجاع
Azizi, Sajad,1404,Numerical Investigation of Rotational Head Impacts in Atrophic Alzheimer's Brains Using Finite Element Analysis,the Ninth international Conference on Sports Science, Physical Education and Social Health,Tehran
ارائهشده در
مجموعه مقالات نهمین کنفرانس بین المللی علوم ورزشی، تربیت بدنی و سلامت اجتماعی31 شهریور 1404 · تهران