چکیده مقاله
Tart cherries are rich in bioactive compounds, such as anthocyanins and other phytochemicals known to have antioxidant properties and exert cardiovascular protective effects However, there is no definitive consensus on this context The present systematic review and meta analysis aimed to investigate the effect of tart cherry juice consumption on cardiovascular disease risk factors A systematic search was conducted on electronic databases, including PubMed, Web of Science, Scopus, and Google Scholar from inception up to December 2021 to identify eligible RCT studies A random effect model was utilized to estimate the weighted mean difference WMD and 95% confidence 95% CI Ten RCTs were included in the present meta analysis The pooled analysis revealed that tart cherry juice consumption led to a significant reduction in the fasting blood sugar FBS levels WMD = 0 51 mg/dl 95% CI: 0 98, 0 06 This lowering effect of FBS was robust in subgroups with cross over studies, participants with age range ≥40, duration of follow up ≤4 weeks, and baseline BMI ≥30 In contrast, tart cherry juice had no effect on total cholesterol TC , triglycerides TG , high density lipoprotein cholesterol HDL C , low density lipoprotein cholesterol LDL C , insulin, body mass index BMI , fat mass, systolic and diastolic blood pressure However, in the subgroup analysis, some significant effects were observed for insulin, TG, TC, LDL C, and HDL C In summary, this meta analysis suggests that tart cherry juice consumption may be beneficial in improving several CVD risk factors However, further RCTs with long term intervention with different dose of administration are needed
کلیدواژهها
نویسندگان
Seyedeh Parisa Moosavian
Department of Community Nutrition, Vice Chancellery for Health, Shiraz University of Medical Sciences, Shiraz, Iran
Maryam maher
Department of Community Nutrition, Vice Chancellery for Health, Shiraz University of Medical Sciences, Shiraz, Iran
Mahla Chambari
Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran
Fateme Moradi
Department of community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
Mehran Rahimlou
Department of Nutrition, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
شیوه ارجاع
Moosavian, Seyedeh Parisa and maher, Maryam and Chambari, Mahla and Moradi, Fateme and Rahimlou, Mehran,1401,Effects of tart cherry juice consumption on cardiovascular disease risk factors: a systematic review and meta-analysis of randomized-controlled trials,Sixth International Conference on Interdisciplinary Studies in Iranian Food Industry and Nutrition Sciences,Tehran
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