چکیده مقاله
Aim: This study aimed to investigate the effects of high intensity interval training HIIT on Adiponectin receptor 1 AdipR1 gene expression in breast tumor tissue and serum levels of glutathione peroxidase GPX and glutathione reductase GR in a murine model of breast cancer Methods: Sixteen male BALB/c mice were inoculated subcutaneously with 4T1 murine mammary carcinoma cells 5 × 105 cells/mouse One week post inoculation, mice were randomly assigned to either a tumor bearing control group Tumor, n=8 or a tumor bearing group subjected to HIIT Tumor HIIT, n=8 The HIIT protocol was performed on a motor driven treadmill five days/week for four weeks, consisting of six 2 minute high intensity intervals 18 25 m/min, 80 90% VO2max interspersed with 3 minute active recovery periods 5 9 m/min Twenty four hours after the final session, tumor tissues were excised for AdipR1 gene expression analysis via quantitative real time PCR 2 AACT method , and serum samples were collected for assessment of GPX and GR levels using ELISA Statistical comparisons were performed using independent samples t tests p
کلیدواژهها
نویسندگان
Samira neshati
Mandana gholamiHosein shirvani
Mandana gholami
Samira neshatiHosein shirvani
Hosein shirvani
Samira neshatiMandana gholami
شیوه ارجاع
neshati, Samira and gholami, Mandana and shirvani, Hosein,1405,High-intensity interval training upregulates adiponectin receptor 1 expression and modulates serum antioxidant enzymes in a Murine model of breast cancer,Tenth international Conference on Sports Science, Physical Education and Social Health,Tehran
ارائهشده در
مجموعه مقالات دهمین کنفرانس بین المللی علوم ورزشی، تربیت بدنی و سلامت اجتماعی31 خرداد 1405 · تهران