چکیده مقاله
Background: Vitamin D and exercise are recognized as important factors in glycemic regulation, yet their combined effects in adults with metabolic disorders have not been sufficiently explored This systematic review and meta analysis aimed to assess the effects of vitamin D supplementation and exercise, alone and in combination, on glycemic control and circulating 25 OH D levels in adults with metabolic disorders Methods: This study followed PRISMA guidelines SCOPUS, PubMed, Web of Science, and Google Scholar were searched up to August 2025 for randomized controlled trials evaluating vitamin D supplementation with or without exercise in adults with metabolic disorders Risk of bias was assessed using Cochrane RoB 2 0, and certainty of evidence was evaluated using GRADE A random effects model was applied using Comprehensive Meta Analysis software version 3 Results: Fifteen randomized controlled trials were included Combined vitamin D supplementation and exercise significantly reduced fasting blood glucose WMD 16 59 mg/dL , fasting insulin 1 54 μU/mL , HbA1c 0 97% , and HOMA IR 0 98 , while increasing serum vitamin D levels 14 39 ng/mL compared with controls all P < 0 05 Subgroup analyses showed improvements in glycemic markers in both aerobic and anaerobic exercise groups, whereas increases in vitamin D levels were more pronounced in the aerobic subgroup Improvements in FBG, HOMA IR, and vitamin D were observed after both 8 and 12 week interventions, while fasting insulin showed significant reduction mainly after 8 weeks Conclusion: Vitamin D supplementation combined with exercise appears more effective than either intervention alone in improving glycemic control and increasing circulating vitamin D levels in adults with metabolic disorders However, further high quality studies are required to confirm and strengthen these findings
کلیدواژهها
نویسندگان
شیوه ارجاع
Pour Ahmadi, Mohammad Javad,1405,Vitamin D and Exercise Effects on Glycemic Control and Vitamin D Status,Tenth international Conference on Sports Science, Physical Education and Social Health,Tehran
ارائهشده در
مجموعه مقالات دهمین کنفرانس بین المللی علوم ورزشی، تربیت بدنی و سلامت اجتماعی31 خرداد 1405 · تهران