چکیده مقاله
Gastric cancer remains a major global health concern, driven by complex interactions among microbial, dietary, genetic, and environmental factors Among emerging preventive approaches, probiotics have shown significant promise due to their ability to modulate gut microbiota, suppress chronic inflammation, and reinforce epithelial barrier integrity This review explores the multifactorial mechanisms by which probiotics may inhibit gastric carcinogenesis, with particular emphasis on Helicobacter pylori eradication, immune regulation, and oncogenic pathway modulation Despite encouraging preclinical and clinical evidence, challenges such as strain specificity, host variability, and safety concerns in vulnerable populations persist Future research should focus on personalized probiotic therapies, integration with conventional treatments, and rigorous clinical validation to establish probiotics as viable agents in gastric cancer prevention
کلیدواژهها
نویسندگان
Sadegh Zomorodimanesh
Bioprocess Engineering Laboratory BPEL , Department of Food Science, Engineering and Technology, Faculty of Agricultural Engineering and Technology, University of Tehran, Karaj, Iran
Seyed Hadi Razavi
Bioprocess Engineering Laboratory BPEL , Department of Food Science, Engineering and Technology, Faculty of Agricultural Engineering and Technology, University of Tehran, Karaj, Iran
Parivash Zomorodimanesh
Bioprocess Engineering Laboratory BPEL , Department of Food Science, Engineering and Technology, Faculty of Agricultural Engineering and Technology, University of Tehran, Karaj, Iran
شیوه ارجاع
Zomorodimanesh, Sadegh and Razavi, Seyed Hadi and Zomorodimanesh, Parivash,1404,The Role of Probiotics in the Prevention of Gastric Cancer,9th International Congress on Food Science & Technology & Agriculture and Food Security,Tehran
ارائهشده در
مجموعه مقالات نهمین کنگره بین المللی علوم و صنایع غذایی، کشاورزی و امنیت غذایی31 شهریور 1404 · تهران