چکیده مقاله
Background: Several studies suggest that vitamin D plays an essential role in the regulation of bone metabolism The aim of the current meta analysis was to assess the effectiveness of vitamin D fortification on special bone biomarkers Methods: Five main databases PubMed/Medline, ISI Web of Knowledge, Science Direct, Scopus, Cochrane Library as well as Science Direct, and Scopus were considered for this systematic review, until January 2020 All randomized controlled trials were included to evaluate the probable relationship between consumption of vitamin D fortification products and bone biomarkers profile in this review Results: Among serum bone biomarkers osteocalcin and telopeptides of type 1 collagen investigated, only the level of telopeptides of type 1 collagen significantly decreased after fortification of vitamin D in the intervention group The significant increase in vitamin D was seen in those older than 18 years old, while the increase in younger children was not statistically significant between intervention and control groups Conclusion: Vitamin D fortification was not associated with a significant improvement in BMD, while it resulted in decreased PTH levels Vitamin D fortified foods have some benefits on bone health due to increase in the level of vitamin D and IGF 1; and decreasing PTH and CTx levels
کلیدواژهها
نویسندگان
Maryam Emadzadeh
Clinical Research Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Atieh Mehdizadeh
Department of Clinical Nutrition, Qaem Educational, Research and Treatment Center, Mashhad University of Medical Sciences, Mashhad, Iran
Payam Sharifan
Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Mahdieh Khoshakhlagh
Department of Medical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Reza Sahebi
Department of Modern Sciences and Technologies, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Ramin Sadeghi
Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
شیوه ارجاع
Emadzadeh, Maryam and Mehdizadeh, Atieh and Sharifan, Payam and Khoshakhlagh, Mahdieh and Sahebi, Reza and Sadeghi, Ramin,1400,The effects of vitamin D fortified products on bone biomarkers: A systematic review and meta-analysis,Fifth International Conference on Interdisciplinary Studies in Iranian Food Industry and Nutrition Sciences,Tehran
ارائهشده در
مجموعه مقالات پنجمین همایش بین المللی مطالعات میان رشته ای در صنایع غذایی و علوم تغذیه ایران26 آبان 1400 · تهران